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Conclusion: IR-780 improved urinary function and complications in rats with pBOO by protecting BSMC mitochondria from oxidative stress, which was potentially mediated through the activation of the Nrf2 pathway

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However, connexin knockout mice experience spontaneous interictal bursts and neuronal hyperexcitability, which has been attributed to decreased buffering of extracellular K + and glutamate (Wallraff et al., 2006

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