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X H NMR (300 MHz, CDCb) δ ppm 7.17 (dd, J=7.08, 8.59 Hz, IH), 6.91 (s, 2H), 6.47 (dt, J=2.55, 8.45 Hz, IH), 6.18 (dd, J=2.64, 12.09 Ηζ, ΙΗ), 5.78-5.91 (m, 2H), 3.78-4.06 (m, 4H), 2.05-2.29 (m, 2H), 2.05-2.29 (m, 2H), 2.20 (quin, J =7.27 Hz, 2H)

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These changes have been implicated in the pathogenesis of neurodegenerative diseases, such as AD and PD [98,99]