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In separate experiments, U937 cells were incubated with 5 ng ml −1 of TNF- α alone or in addition to 20 mM of GSH and U937-hGH cells were incubated with 5 ng ml −1 TNF- α alone or in addition to 50 mM of diethyl maleate (DEM) (Sigma), in conditions already used in our models (Déas et al, 1997)