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Cellular Compartmentalization, Glutathione Transport and Its Relevance in Some Pathologies - PMC

e-mail: [email protected] This article was submitted to Frontiers in Plant Proteomics, a specialty of Frontiers in Plant Science

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For example, curcumin has been evaluated in Phase II clinical studies in pancreatic cancer and colorectal cancer patients, where oral doses up to 8 g/day demonstrated acceptable safety but limited systemic exposure, highlighting pharmacokinetic challenges