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For works cited in this article, biomarkers such as total antioxidant capacity (TAC), which was measured by colorimetric method, MDA [30,31], which was tested quantitatively by reaction with thiobarbituric acid reactive substance (TBARS) [30], and malondialdehyde-LDL (MDA-LDL) [32] were used (among others) to assess oxidative stress

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E.g., if a receptor has more than one binding site for a ligand, a ligand having low affinity can be useful for targeting the microvascular endothelium