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🧪 Glutathione Depletion Pathways 1. Precursor Depletion - Key bottleneck: Cysteine availability. - Source: Diet or hepatic transsulfuration (methionine → homocysteine → cysteine). - Failure mode: Downregulation of cystathionine γ‑lyase (CSE) during

Utilizing Superoxide Dismutase Mimetics to Enhance Radiation Therapy Response While Protecting Normal Tissues

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Without equitable access and regulatory access to these innovations, we risk their use becoming exclusively available through payment, making them only available to a select and elite cohort of the population, thus compounding health discrepancies

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