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Glutathione in the deproteinized fraction and protein-bound fraction of plasma were determined using the method described by Park et al

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Oral intoxication with Cuprizone leads to myelin degeneration, microgliosis, astrogliosis and axonal damage [3,4,5,6] in various central nervous system regions, such as the corpus callosum, cortex or hippocampal formation [7,8,9]