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Clinical translation and emerging therapeutic applications of intranasal drug delivery systems In recent years, there has been a notable increase in the clinical translation of advanced intranasal delivery technologies, particularly those designed to overcome limitations associated with conventional nasal sprays, such as anterior deposition, post-nasal drip, and inconsistent dosing due to nasal valve obstruction

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Given the difference in metabolism between humans and rodents, it is premature to determine whether 3DM has toxic effects in humans