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Peroxisome proliferator-activated receptor alpha (PPARα) is a key transcription factor that regulates genes involved in mitochondrial FA oxidation [28]

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As already stated, the series-2 prostaglandin precursor, PGH 2 gives rise to a number of prostanoids, such as PGD 2 , PGE 2 PGF 2α , PGI 2 and thromboxane A 2 (TxA 2 ) [94], through tissue-specific isomerisation to produce the diverse prostanoids which exert wide range of biological effects upon interaction with specific G-protein coupled receptors [96]