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The concern is dosing accuracy, not safety

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FIGURE 1 2.4 Subacute oral toxicity study Subacute oral toxicity study was performed based on the guidelines provided by the Organisation for Economic Co-operation and Development No.407 (OECD 407), Repeated Dose 28-day Oral Toxicity Study in Rodents ( n = 5–6/gender/group), was administered with vehicle MediGel via voluntary oral administration