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Conclusion The form of lipid peroxidation with the result of molecular oxygen conversion to ROS with various environmental factors particularly smoking cigarette, alcohol, UV rays, and other oxidants leads to oxidative stress

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In an in vitro study on microglial cells, PYC dose-dependently decreased the release of nitric oxide, tumor necrosis factor-α (TNF-α), interleukin (IL)-6, IL-1β, ICAM-1, and perilipin 2, thereby exhibiting anti-inflammatory activity (Fan et al., 2015)