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Mutations in the TF gene increase iron absorption and neurotoxicity, whereas deletion of TfR2 has been shown to protect against dopaminergic neurodegeneration (Mastroberardino et al., 2009

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Oxidative stress, resulting from the duration and severity of exposure to pro-oxidant molecules and antioxidant defenses, can damage the ovarian reserve and adversely affect oocyte and subsequent embryo development

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