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[DOI] [PubMed] [Google Scholar] Morse MA, Lu J, Gopalakrishnan R, Peterson LA, D'Ambrosio SM, Wani G, et al

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Schumacher et al., 2021) potentially decreasing cancer incidence early in life through preventing proliferation of damaged cells, but driving aging related degeneration later in life through SASP which can maintain proinflammatory milieu and cause paracrine senescence, leading to decrease in tissue proliferative potential (Nelson et al., 2012)