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In vitro , in a colon epithelial cell line (Caco-2), TNFα-induced increases in TJ permeability were associated with increased nuclear factor kappa beta (NF-κB) activation and nuclear translocation of NF-κB p65 [13]

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Evidence of secondary coenzyme Q 10 deficiency has been reported in several mitochondrial disorders, such as mitochondrial DNA depletion syndrome, Kearns-Sayre syndrome, or multiple acyl-CoA dehydrogenase deficiency (MADD) (10)