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From the view of selenium forms, the inorganic forms (such as sodium selenate and sodium selenite) of selenium were more effective on increasing the GPX activity compared with selenomethionine [44]

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Concurrently, the E3 ligase ZNRF2 tunes the ubiquitination of the auxiliary subunit SLC3A2 at K147, driving its plasma membrane translocation to maximize cystine import in lung adenocarcinoma, which can be therapeutically blocked by the synthetic peptide K147 [36]