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In postmortem central nervous system tissues from ALS patients, particularly in lower motor neurons, reduced levels of 5mC and 5hmC have been observed, correlating with the presence of TDP-43 proteinopathies (150)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Lee S.H., Whon T.W., Roh S.W., Jeon C.O