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Causes of small fiber neuropathy include idiopathic (30% of cases — no identifiable cause), diabetes and pre-diabetes (impaired glucose tolerance), autoimmune diseases (Sjogren’s syndrome, celiac disease, lupus), genetic causes (sodium channel gene mutations — SCN9A, SCN10A), and sarcoidosis

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Cross-talk between GSH and other signaling molecules would be anticipated during adaptation to abiotic stress, but this aspect is still poorly studied