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The complexity of AD pathogenesis lies in its convergence of interdependent pathological processes, including oxidative stress, chronic neuroinflammation, mitochondrial dysfunction, and impaired autophagy (Park et al., 2022)

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All these factors converge in a common activation of systemic inflammation, which contributes to disease progression and to the onset of other pathologic states such as CVD

inflammatory hepatitis (including hepatic lipidosis)