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Morin (3,5,7,2',4'-Pentahydroxyflavone) Abolishes Nuclear factor-kappaB Activation Induced by Various Carcinogens and Inflammatory Stimuli, Leading to Suppression of Nuclear factor-kappaB-Regulated Gene Expression and Up-Regulation of Apoptosis

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COX-2 modulated lipid peroxidation and oxidative stress in TAA-induced chronic liver injury and erastin-induced hepatocyte ferroptosis Lipid peroxidation is pivotal for initiating ferroptosis, and polyunsaturated fatty acids are the most susceptible lipids in peroxidation, such as arachidonic acid (AA, C20:4), adrenic acid (AdA, C22:4), linoleic acid (Lin, C18:2), and C22:6