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Icariin interacts with IGFBP3 to alleviate diabetic cataract through PI3K/AKT signaling pathway - ScienceDirect

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The mechanism of demethylation lies in the fact that it can reduce the expression of DNMT1 and inhibit the acetylation of STAT3, which can destroy the interaction between acetylated STAT3 and DNMT, thus inhibiting CpG methylation ( A total of 24 patients with relapsed or refractory multiple myeloma were enrolled in a phase II clinical trial