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After a few weeks, a final lock-in of the IOL power is achieved [187]

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98,99 Their advantages include: (1) the improved bioavailability of insoluble drugs and reduced side effects, (2) the protection of their cargo from degradation and rapid clearance, (3) specific tissue targeting using surface-coupled ligands, (4) controlled drug release and (5) co-delivery of agents for a synergistic therapeutic effect