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Meta-analyses of clinical studies have shown that curcumin supplementation leads to a reduction in inflammatory markers, such as C-reactive protein (CRP) and the erythrocyte sedimentation rate (ESR), and improves clinical outcomes, including a decrease in the number of swollen and tender joints and an improvement in the DAS28 disease activity index

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Choi, Molecular Insights into NR4A2(Nurr1): an Emerging Target for Neuroprotective Therapy Against Neuroinflammation and Neuronal Cell Death, Molecular Neurobiology (2019)