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In this context, citrate is transported out of the mitochondria into the cytosol via the mitochondrial citrate carrier SLC25a1 and - with the help of ATP citrate lyase – functions as an acetyl donor to support the generation of acetyl CoA and fatty acid-derived derivatives

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Allergen exposure in allergic asthma promotes the activation of leukocytes, especially eosinophils and neutrophils, and NADPH oxidase