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doi: 10.1016/j.fct.2012.12.041 [DOI] [PubMed] [Google Scholar]

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In our study, we found that after 14 consecutive days of curculigoside (CUR) treatment, the spatial memory was improved in the mice model of learned helplessness (LH), and extinction of fear memory was also accelerated by promoting the expression of BDNF in the hippocampus through activating the AKT-mTOR signaling pathway [90] (Fig