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Fixation and Permeabilization Most signaling takes place intracellularly, meaning that cells need to be fixed and permeabilized to allow detection antibodies to reach their targets

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The ∆sodC and sodB ∆sodC mutants were also significantly attenuated for virulence in intranasally challenged C57BL/6 mice compared to the wild-type LVS, indicating that SOD-C is required for resisting host-generated ROS and contribute to survival and virulence of in mice [119]