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Vitamin C is an antioxidant that brightens and protects against free radicals, while tranexamic acid works on the melanin pathway to reduce dark spots

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7,9 However, as shown in Supplementary Figure, a couple of compounds with free thiol group and disulfide bond are present in the low-molecular-weight fraction of rat plasma, which can react with Ellman’s reagent and provide apparent values for glutathione and its disulfide