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In this regard, future research areas concerning the use of semaglutide and tirzepatide in patients with autoimmune diabetes (including pediatric patients) are the following: Investigation of the safety and efficacy of semaglutide and tirzepatide used as non-insulin adjunct therapies in patients with new-onset and long-standing T1D (stages 3 and 4 T1D) for preserving residual beta-cell function, improving glucose control, reducing daily insulin requirements (in terms of both basal and bolus insulin doses), prolonging the honeymoon phase, and preventing or treating excess body weight