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AM-36 is a neuroprotective agent that combines antioxidant and Na + channel blockade properties ( 3.2 Parkinson’s disease Parkinson’s disease (PD) is a common neurodegenerative condition distinguished by the progressive degeneration of dopaminergic cells in the substantia nigra, a region in the midbrain known for its accumulation of synuclein (Poewe et al., 2017)

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Melatonin inhibits the ferroptosis pathway in rat bone marrow mesenchymal stem cells by activating the PI3K/AKT/mTOR signaling axis to attenuate steroid-induced osteoporosis