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Oxidative stress activates multiple transcription factors, including hypoxia-inducible factor-1α (HIF-1α), AP-1, NF-κB, p53, and nuclear factor erythroid 2-related factor 2 (Nrf2) (Reuter et al., 2010)

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Potential Side Effects and Considerations While glutathione is generally safe, it is not entirely without side effects