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Semax appears to modulate neuropeptide signaling in the hypothalamus, reduce oxidative stress in gonadal tissue, and restore balance in HPA and hypothalamic-pituitary-gonadal (HPG) axes

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Finally, we examine a number of alternative, safer strategies that are under investigation to harness the therapeutic potential of HO-1, including the use of phytochemicals, novel HO-1 inducers and carbon monoxide-based therapies