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However, it fails to complete this function when a highly conserved isoleucine in the FH2 domain is mutated (hereafter, referred to as the IA mutation) (Kutscheidt et al., 2014)

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Further, in older sarcopenic adults, a 12-week RT program (3 times per week of full body RT at 75% 1RM) was shown to reduce sleep latency (shorter time necessary to fall asleep) as well as increase time spent in slow-wave sleep, when a large proportion of glymphatic drainage and restorative processes occur ( Resistance exercise as a unique hemodynamic stressor From a vascular perspective, the hemodynamic stimulus associated with resistance exercise, particularly at high intensities is unique, characterized by high magnitude and rapid oscillations in blood pressure (Perry and Lucas, 2021)

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