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In the afferent direction, area postrema is dense with mast cells (Figure 1) in order for signal to be detected ( Figure 1 Because neuroinflammation can affect normal function and structure, even methods that do not directly measure neuroinflammation (e.g., fMRI and structural MR) can be clarifying if their focus is on neuroinflammation-relevant brain circuits and structures

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for instance, the latter two sections are largely derivative of single sources.” Response: We have added a section titled “General treatment approaches” appearing at the end of the article, before the concluding remarks

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