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Specifically, a review of clinical trials on the use of BPC-157 has characterized it as safe both in treating inflammatory bowel disease and wound healing, noting that no events of toxicity had been reported throughout those trials [12]

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(83) found that C3G treatment did not alter the expression levels of collagen type I alpha 1 chain (Col1α1) and Runx2 but promoted bone formation by enhancing the expression of downstream osteogenic differentiation marker genes (OPN, OCN, ALP) and the key transcription factor Osx