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SNR #129: Chris Masterjohn, PhD - Glycation, Oxidative Stress & The Protective Effects of Glucose and Insulin - Sigma Nutrition

C.HayashiK.et al (2023)

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Supplementary material The Supplementary Material for this article can be found online at: Glossary OP Osteoporosis OA Osteoarthritis RA Rheumatoid arthritis VC Vitamin C GULO L-gulonolactone oxidase DHA Dehydroascorbic acid SVCTs Sodium-dependent vitamin C transporters MuSCs Muscle stem cells BMSCs Bone marrow mesenchymal stem cells MRFs Myogenic regulatory factors MyoD Myoblast determination protein 1 Myf5 Myogenic factor 5 MyoG Myogenin CSRP3 Cysteine and glycine-rich protein 3 ERK Extracellular signal-regulated kinase IGF-1 Insulin-like growth factor-I KDM7A Lysine demethylase 7A TET Ten-eleven translocation mTOR Mechanistic target of rapamycin PI3K Phosphoinositide 3-kinase Akt Protein kinase B p70S6K p70 ribosomal S6 kinase Pax7 Paired box protein 7 ECM Extracellular matrix ALP Alkaline phosphatase BMP-2 Bone morphogenetic protein-2 COL-I Type I collagen OCN Osteocalcin BMD Bone mineral density Osx Osterix PHD Prolyl hydroxylase domain EB1 End-binding protein 1 Runx2 Runt-related transcription factor 2 BSP Bone sialoprotein MMPs Matrix metalloproteinases RANKL Receptor activator of nuclear factor κB ligand NF-κB Nuclear factor kappa B TRAP Tartrate-resistant acid phosphatase SOX9 SRY-box transcription factor 9 ACAN Aggrecan COMP Cartilage oligomeric matrix protein HIF-1α Hypoxia-inducible factor 1α ROS Reactive oxygen species OPN Osteopontin TNF-α Tumor necrosis factor-α CaMKIIα Calcium/calmodulin-dependent serine/threonine kinase IIα CREB cAMP-response element-binding protein ATF4 Activating transcription factor 4 MAPK Mitogen-activated protein kinase TGF-β Transforming growth factor-β STAT3 Signal transducer and activator of transcription 3 NLRP3 NLR family pyrin domain-containing 3 FOXO1 Forkhead box O1 MAFbx Atrogin-1/muscle atrophy F-box MuRF1 Muscle RING finger 1 MDA Malondialdehyde CRP C-reactive protein References 1 BaroneRSzychlinskaMA