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11 However, these claims appear to be based on one review of 41 cases of SS from 1995 to 1999, 12 and in a more recent meta-analysis, just more than 60% presented within 6 hours of ingestion (usually where pro-serotonergic drugs were administered quickly or in large doses including overdose), while around one quarter of patients presented later than 24 hours (usually when medication were more gradually titrated and/or cross-tapered)

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