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In contrast, 1907 demonstrated two binding sites ( K D1 = 0.8 ± 0.6 µM, K D2 = 8.7 ± 3.3 µM), with a 100-fold increased affinity over LD2, and a tenfold improved K i of 5.8 ± 4.6 µM by FP (Table 1 and Fig

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Abstract Cartilage repair after degeneration or trauma continues to be a challenge both in the clinic and for scientific research due to the limited regenerative capacity of this tissue

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