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In the brain, it serves several key roles: Primary antioxidant defense against ROS Toxin Clearance support , binding and helping remove certain toxins and heavy metals Mitochondrial protection , helping maintain energy production Regulation of cell survival and repair , including controlled cell death (apoptosis) Support for other antioxidants , including vitamins C and E Glutathione exists in two main forms: GSH (reduced glutathione) - the active, protective form GSSG (oxidized glutathione) - the βusedβ form after neutralizing free radicals The ratio of GSH to GSSG is a sensitive indicator of cellular redox balance
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