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Its epidemiology shows marked geographic variation: incidence is highest in North America and Western Europe (9–20 cases per 100,000 person-years) but is rising rapidly in regions historically considered low risk, including parts of Asia and South America (Hracs et al., 2025

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Quantification of apoptotic cells revealed that there was a significant reduction in CGN apoptosis with Immunocal pretreatment compared to CGNs treated with CuCl 2 alone (Figure 3(b))