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GHK-Cu has been studied across multiple research domains including wound healing (accelerated closure, improved collagen architecture), skin remodelling (upregulation of collagen types I and III, elastin, glycosaminoglycans), hair follicle stimulation (increased follicle size, anagen extension), antioxidant defence (SOD and catalase upregulation), and gene expression regulation (modulation of over 4,000 genes in genomic analysis)

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HGF protects endothelial cells against apoptosis in cerebral ischemia animal models and prevents the associated learning and memory dysfunctions (Takeo et al., 2008)