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Data availability The data generated and analyzed during the current study are available in the figures and supplementary materials, and have been deposited in a citable, publicly accessible repository (Mendeley data: Ethics statement All animal procedures were conducted in accordance with the National Guidelines for the Regulation of the Use of Experimental Laboratory Animals from the Generalitat de Catalunya and the Government of Spain (Article 33.a, 214/1997) and approved by the University of Lleida Experimental Animal Ethics Committee (CEEA)

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50 On the other hand, HLA-DRB1*14:06 was significantly more frequent in pSS patients than in those with sSS