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After 24 weeks of treatment, there was a 30% reduction in new DUs in the bosentan group

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Size:40ml

When compared to the control group, SSc patients with the TBX21 CC genotype exhibited increased levels of IL-6 and tumor necrosis TNF-α, whereas those with the TT genotype demonstrated elevated levels of interleukins IL-2, IL-5, IL-4, and IL-13, indicative of a Th2 response