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Similarly, defects in cystathionine synthase, which converts homocysteine to cysteine, leads to elevated 5-oxoproline levels as well

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Consistent with AsPC-1 cells (Figures S2A and S2B), deoxycarnitine and dimethylarginine were depleted in cells lacking the transporter, while SLC25A45 KO OVCAR-3 cells also accumulated intracellular trimethyllysine (Figures S8C and S8D