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Fisetin treatment significantly decreased SA-β-Gal+ and GL13+ (lipofuscin) senescent neurons, astrocytes, and microglia in both grey and white matter of the cerebral brain cortex and non-Cornu Ammonis area of the hippocampus of old sheep

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Professor Moses Elisaf has received speaker honoraria, consulting fees, and research funding from AstraZeneca, Schering Plough, Merck, Pfizer, Solvay, Abbott, Boehringer Ingelheim, and Fournier, and has participated in clinical trials with AstraZeneca, Merck, Sanofi-Synthelabo, Solvay, Glaxo, Novartis, Pfizer, and Fournier