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This event leads to the release of cytochrome c, enabling the formation of the apoptosome (formed by caspase 9, Apaf-1 and cytochrome c), followed by the activation of caspase 3, ultimately causing cellular membrane disassembly [183]

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Weight:450ml

Due to these genetic alterations, the rd1 retina suffers metabolic disturbances that through various mechanisms cause degeneration of rods 36