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found that human liver NNMT had Km values of 430 and 1.8 μM for NAM and SAM respectively by using the radiochemical enzymatic assay at 37 °C, which is based on the conversion of NAM to radioactively labeled 1-MNAM with [methyl- 14 C]-SAM as the methyl donor [5]
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Quantity:Subscribe: 120 Days Supply
People who may not get enough vitamin B12 or who have trouble absorbing it include: Many older adults People who don’t make enough hydrochloric acid and intrinsic factor in their stomachs People with pernicious anemia People who have had some types of stomach or intestinal surgery People with digestive disorders, such as celiac disease or Crohn’s disease People who follow a vegetarian or vegan eating plan Signs of B12 deficiency Weakness, fatigue, heart palpitations, appetite loss, weight loss, and numbness or tingling in the hands or feet (signs of nerve problems), depression, confusion, dementia, and soreness of the tongue or mouth are signs of a possible vitamin B12 deficiency
