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A striking property of SetCys is its conversion to a native Cys residue by cleavage of a nitrogen–carbon bond under extremely mild conditions if a strong reducing agent is present in the solution

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We observed that glucose deprivation resulted in a significant decrease in GPx1 protein levels compared with superoxide dismutase (SOD1), whereas the levels of peroxisomal catalase (CAT) and paraoxonase (PON1) were not significantly altered (Supplementary Figure S6)