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DSIP capsules require formulation technology to protect DSIP from gastrointestinal enzymatic hydrolysis and promote its passage through the intestinal mucosa and blood-brain barrier, thereby exerting central nervous system regulatory effects

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thus, the adaptability and survival of MSCs within IVDs require further study ( Human clinical trials have predominantly focused on MSCs owing to the promising outcomes exhibited by MSCs in reducing pain and improving function in patients with IVD degeneration (Table 1)