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Furthermore, defelikefalin (korsuva, a pain-relieving opioid peptide for moderate to severe itching), approved by the FDA in 2021, uses a full D-amino acid (D-Phe, D-Leu, D-Lys) strategy

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Next, the attenuation in calf was confirmed and the capacity of these candidate vaccines to induce immune responses in the natural host was evaluated in the calf model ( Figure 1C )