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38 Expert Consultation We engaged with experts in the specialty areas of pharmacogenetics, clinical oncology, and laboratory medicine to help inform our understanding of aspects of the health technology and our methodologies, and to contextualize the evidence

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These FAHFAs can be stored as TAGs (156) and mobilized during cold exposure by PNPLA2 to promote de-novo lipogenesis and FA-esterification in an insulin-independent manner (157), possibly explaining the coupling of lipolysis to lipogenesis in adipocytes (151)