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While you can supplement with a bit more than this (many supplements have 15 to 30 mg), you should not exceed the tolerable upper intake of 40 mg per day from food and supplements combined, unless supervised by a doctor

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Second, while the 3-week treatment period demonstrated efficacy using the well-validated CMS model, longer-term studies are needed to evaluate sustained effects and chronic toxicity, as dedicated safety assessments (e.g., histopathology, clinical chemistry) were not conducted in this investigation